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Methods: Independent randomized crossover clinical studies were conducted to assess AL, including subjective effects (product liking [PL], urge to smoke, product effects, overall PL, and overall intent to use again) and nicotine pharmacokinetic (PK) parameters of Velo ONPs

Inability to stop using tobacco products, despite making attempts to quit Continuing using tobacco products despite health problems Strong cravings for tobacco Withdrawal symptoms when trying to quit Giving up activities or refusing to attend events/places where tobacco use is not allowed Using tobacco products to deal with stress or feel normal Gradually increasing tobacco use Spending most of the time during the day using tobacco products, at home, work, and other places Tobacco products are legal, easily obtained, and people can consume them in public

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See that work in action, in the videos above.